Welcome to the research lab of David Sept in the
Department of Biomedical Engineering at the University of
Michigan in Ann Arbor, Michigan.
Our lab is interested in understanding the dynamics, function and organization of the
cytoskeleton, in particular the molecular details underlying cell motility, and the
structure, dynamics and interaction of microtubules. In order to determine how actin
filaments, microtubules, and their associated proteins work within the cell, we feel it
is important to first understand the interactions that occur at the molecular level. We also
perform work in the area of drug/inhibitor design, nanoparticle pharmacokinetics and
ligand gating in potassium channels. What makes all this research possible is the
combination of advances in the fields of computer science and structural
biology/biochemistry. See the research page for more detailed
If you are looking for information and files relating to our multisite ion models, you
can find those details here.